Description

Scientist I, Analytical Development

Location: Cambridge, MA

Requisition Number: 469

How will your role help us transform hope into reality?

This position will contribute to the analytical development strategies and deliverables for small molecule drug substances (DS) and drug products (DP) of one or more projects in development from pre-clinical through post approval lifecycle management.  This person will define and execute experimental plans internally and in  collaboration with external laboratories to ensure appropriate control strategies are in place.  This individual will also be responsible for authoring, reviewing, and/or approving internal and external reports, including but not limited to method development, method validation, investigation, and justification of specification reports as well as the appropriate analytical regulatory sections.

What will you do?

• Address the analytical needs of drug substances (DS) and drug products (DP) in development from pre-clinical to product launch
• Solve technical issues and provide technical direction to experiments performed both internally and at external laboratories
• Design and manage the method development, validation, and transfer activities executed internally and through the management of external CMO partners
• Influence the development of phase appropriate control strategies in collaboration with key stakeholders
• Prepare presentations and reports to communicate results to project teams and senior leadership as required
• Author, review, and/or approve analytical protocols and technical reports
• Author, manage, and/or review pertinent Analytical Development related sections of regulatory submissions

What minimum qualifications do we require?

• Ph.D. in analytical  chemistry or related discipline with 1 year of relevant small molecule pharmaceutical development experience, or a BS/MS in chemistry with 5 years of relevant small molecule development experience

What additional qualifications will make you a stronger candidate?

• Demonstrated knowledge of analytical technologies
• Demonstrated knowledge of regulatory requirements and guidelines (cGMP, ICH, FDA, and USP) and the ability to apply the guidelines consistent to the stage of pharmaceutical development
• Resourcefulness/Flexibility – The ability to adapt to working optimally within a variety of situations; adapts to change and to changes in job demands
• Communication and Partnership – Ability to optimally express ideas in written and oral context; collaboration, team-building skills and interpersonal skills; genuine desire to be on a team and contribute to organizational and team goals
• Effective Planning – Demonstrated effective time management skills and execution
• Perseverance – Pursues tasks with energy, drive and initiative; comfortable in an accountable environment where you can make an impact
• Problem Solving – Ability to understand a situation or problem by breaking it down into smaller pieces using a detailed approach and to identify patterns and connections between situations that are not obviously related
• Relationship Building – Builds productive working relationships across a diverse spectrum of people
• Commitment to our Core Values: Patients First, Thoughtfulness, Urgency, Trust, Optimism

COVID-19 Vaccination Requirement

As a biotechnology organization, it is our responsibility to do everything we can to safeguard the health and safety of our workforce, our communities, and the patients we serve.  That is why, prior to their start date, new hires must provide confirmation that they are fully vaccinated against COVID-19, or be approved by Blueprint for an exemption for health reasons contraindicating the vaccines or sincerely held religious beliefs.  Accommodation requests for either of these reasons should be made to TotalRewards@blueprintmedicines.com.

Equity, Diversity, Inclusion and Affirmative Action

At Blueprint Medicines, we foster a culture of equity, diversity and inclusion.  A proud Equal Employment Opportunity and Affirmative Action employer, we consider all qualified applicants without regard to race, color, sex, gender identity or expression, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable law.  We are also an E-Verify Employer.  We will make reasonable accommodations, absent undue hardship, for qualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with the application or recruiting process, please reach out to TotalRewards@blueprintmedicines.com. 

For more information, please see our EEO-AA Policy Statement, the EEO Know Your Rights Poster, as well as our Pay Transparency Statement. 

Blueprint Medicines is a global precision therapy company that invents life-changing therapies for people with cancer and blood disorders. Applying an approach that is both precise and agile, we create medicines that selectively target genetic drivers, with the goal of staying one step ahead across stages of disease. Since 2011, we have leveraged our research platform, including expertise in molecular targeting and world-class drug design capabilities, torapidly and reproducibly translate science into a broad pipeline of precision therapies. Today, we are delivering approved medicines directly to patients in the United States and Europe, and we are globally advancing multiple programs for systemic mastocytosis, lung cancer and other genomically defined cancers, and cancer immunotherapy. For more information, visit www.BlueprintMedicines.com and follow us on Twitter (@BlueprintMeds) and LinkedIn.